Which protein should have its N-terminus facing the cytosol and its C-terminus facing the lysosome lumen?

Which protein should have its N-terminus facing the cytosol and its C-terminus facing the lysosome lumen?

Which protein should have its N-terminus facing the cytosol and its C-terminus facing the lysosome lumen? 150 150 Nyagu

Question Description
I’m working on a biology question and need an explanation to help me learn.

The following shows the predicted domains for different proteins. “Signal” refers to an ER signal sequence, “++” refers to positively charged amino acids, and “–” refers to negatively charged amino acids. Which protein should have its N-terminus facing the cytosol and its C-terminus facing the lysosome lumen?

Protein 3

Protein 4

Protein 1

Protein 2

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