PATH30190 Oncology & Immunopathology

PATH30190 Oncology & Immunopathology

PATH30190 Oncology & Immunopathology 150 150 Peter

PATH30190 Oncology & Immunopathology

Academic Year 2021/2022

The Oncology and Immunopathology Module (PATH30190) reviews the biochemical and molecular processes underlying neoplastic diseases and the pharmacologic agents used to intervene in these processes through lectures, tutorials and online British Medical Journal (BMJ) tutorial submissions.

This module covers the basic pathology of cancer to include tumour classification and terminology, invasion and metastasis and molecular carcinogenesis. The pathology of tumours of the breast, bone and soft tissues, the skin (malignant melanoma and non-melanoma skin cancers) and childhood tumours are included, as are chemotherapeutic and biotherapeutic agents, including targeted therapies, monoclonal antibody therapies and an introduction to the care of the patient with cancer, including the management of side effects of chemotherapy.

Immunopathology processes are reviewed with special emphasis being placed on the mechanisms underlying hypersensitivity reactions, autoimmunity, transplantation and rejection. In addition, the clinical presentation, pathology and treatment of systemic autoimmune diseases (including rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis and various systemic vasculitides) are discussed. The pharmacology of anti-inflammatory and immunosuppressive agents are also reviewed.

The clinical presentation, behaviour and pharmacological management of these inflammatory, immunologic and neoplastic diseases are introduced together with clinicopathological correlation and elementary planning and evaluation of treatment through lectures and tutorials.

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