PATH30070 Mechanisms of Disease
Academic Year 2021/2022
The Mechanisms of Disease module forms part of the core curriculum for students of the B.Sc. in Diagnostic Imaging programme.
The module begins by describing basic mechanisms of cellular injury and adaptation, cell death, inflammation and tissue repair. It then sequentially addresses the general pathophysiology of immune disorders, genetic diseases, neoplasia, environmental and nutritional disorders and vascular disease.
On successful completion of the module, students should be able to;
1) Discuss the mechanisms, pathological features and complications of cellular adaptation, cell injury and cell death.
2) Describe the aetiology, pathophysiology and complications of acute and chronic inflammatory responses.
3) Using specific examples, outline the basis of autoimmunity and immunodeficiency and describe the role of the immune system in transplantation.
4) Outline the basis by which genetic abnormalities can give rise to disease.
5) Discuss the pathogenesis and pathology of benign and malignant neoplastic disease.
6) Have an insight into the effects of environmental factors on the pathology of disease.
6) Provide an overview of the underlying pathological process ongoing using specific case-based examples of disease and from the perspective of diagnostic imaging.
Indicative Module Content:
Pathology, Mechanisms of disease – Cell injury, Cancer, Inflammation, Genetics
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