PATH10020 Basic Principles of Cell Biology
Academic Year 2021/2022
This is a foundation module forming part of the core curriculum for Stage 1 Medicine students, Biomedical Health and Life Science students and also Stage 1 Human Nutrition students. This module is designed to give students an overview of how cells work, exploring the different cellular organelles, the structure and function of nucleic acids and proteins, cell cycle and cell death, cell communication and signalling pathways relevant to disease. Basic principles of cellular immunology will also be introduced.
Please note all students in the BSc Science program (year 2 and above) should contact the Module Co-ordinator before registering for this module as an elective.
On completion of this module, students should be able to:
Describe the basic structure and function of the human cell and display an understanding of the fundamental components of a mammalian cell.
Describe the basic structure and functions of nucleic acid and demonstrate how alterations in DNA sequence cause disease.
Demonstrate an understanding of protein structure and post-translational modifications.
Discuss the intra- and extra-cellular signalling mechanisms of a cell and understand the implication of cell signalling in disease.
Explain cell division, cell cycle and cell death and it’s involvement in disease.
Review the fundamentals of cellular immunology.
Indicative Module Content:
Mammalian cell organelles
DNA and RNA structure, DNA replication, transcription and translation
Protein structure and function
Cell communication and cell signalling
Cell division, cell cycle, cell death
Innate and adaptive immunity
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