NSG5003 Week 10 Discussion Essay Sample
NSG5003 Week 10 Discussion Essay Sample
PAGE 1: Explain the action of thyroid hormone. Your answer should contain the impact of the thyroid hormone on functions in the body. PAGE 2: (1)Discuss the negative feedback loop of thyroid function.(2)Select either hypothyroidism or hyperthyroidism and define the clinic presentation providing the pathophysiologic process underlying the clinical presentation.
Week 10 Discussion
Explain the action of thyroid hormone. Your answer should contain the impact of the thyroid hormone on functions in the body.
Nearly all organs and systems in the body, such as the cardiovascular system, reproductive system, and the nervous system are affected by the thyroid hormone. In human body, it circulates in the form of triiodothyronine and thyroxine. NSG5003 Week 10 Discussion Essay Sample. Hypothyroidism, associated with exhaustion, reproductive problems, and hair loss is the outcome of low thyroid hormone levels (Young, 2011). Hyperthyroidism arises as a result of elevated levels of circulating thyroid hormone and is associated with nervousness, insomnia, anxiety, and higher heart rate. Researches have demonstrated that thyroid hormone affects the metabolic rate of the body, which when elevated, results in higher body temperature because of higher rate of hydrolysis of ATP and oxygen consumption(Chiellini et al., 2019).
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In addition, elevated levels of thyroid hormone result in fatty acid oxidation and lipid metabolism in the organs of the body. It also enhances the cardiac contractility, standard development of infants, heart rate, cardiac output, and metabolism of carbohydrates. The level of thyroid hormone is similarly impacts the human brain, with a low level triggering mental unresponsiveness and an elevated level leading to nervousness and anxiety. Human and animal reproduction relies on thyroid hormone with hypothyroidism causing infertility. NSG5003 Week 10 Discussion Essay Sample
Discuss the negative feedback loop of thyroid function
A pituitary hormone that stimulates the thyroid gland to secrete triiodothyronine and tyrosine which affects all organs and systems in the body is the thyroid stimulating hormone. Thyrotropin releasing hormone (TRH) is produced by the hypothalamus, which triggers the pituitary gland to release thyroid stimulating hormone (TSH). It stimulates the thyroid gland to produce thyroid hormones, in exchange (Kleine&Rossmanith,2016). When the level of thyroid hormone is higher than usual, the hormones respond to prevent TSH from being released by the pituitary gland and TRH from being secreted by the hypothalamus. The thyroid gland regulates the release of hormones without activation of TSH, and eventually the thyroid hormone level begins to collapse back to its normal level. The opposite occurs when the thyroid hormone level drops below the normal level.
Clinical presentation and the pathophysiologic process of hypothyroidism
Primary hypothyroidism induces a rise in the stimuli of the anterior pituitary gland, which leads to an increase in TSH development leading to a decline in T3 and T4 thyroid hormone secretion (Huether, &McCance, 2017). However, secondary hypothyroidism develops when the hypothalamus releases an inadequate quantity of thyrotropin, or when the anterior pituitary develops insufficient TSH. The equilibrium in the output of these hormones is very critical and essential for appropriate growth of the nervous system and for skeletal development, which can result in severe derangement and impaired development in children if it remains untreated. The clinical presentation of hypothyroidism is typically seen in the body and escalates over time. Due to a decreased level of TH (Thyroid Hormone), the person will have reduced energy levels as well as low body temperature (Huether,&McCance, 2017). Some symptoms of hypothyroidism including: cold aversion, memory problems, constipation, , exhaustion, edema, and excess weight attributable to a slow metabolic rate. NSG5003 Week 10 Discussion Essay Sample
Chiellini, G., Cioffi, F., Senese, R., & Lange, P. D. (2019). Thyroid Hormone and Metabolites: Central Versus Peripheral Effects. Lausanne, Switzerland: Frontiers Media SA.
Huether, S.E., McCance, K. L (2017). Alterations of Hormone Regulation.In V.L.
Kleine, B., &Rossmanith, W. G. (2016). Hormones and the Endocrine System: Textbook of Endocrinology. Basingstoke, England: Springer. NSG5003 Week 10 Discussion Essay Sample