BMOL40190 Multicellular Systems

Academic Year 2021/2022

Nearly all life science research is based on the use of multicellular systems, the model used depending on the field of research and the type of question to be answered. However, there is no such thing as a “perfect” model. It is therefore essential to understand the potential as well as the limitations of each model system. Moreover, nowadays additive manufacturing techniques such as 3D bioprinting offers the possibility to print tissue “at will”. In this module we will discuss in an inverted lecture context the pros and cons of major and minor model systems as well as investigating tissue engineering methodologies. We will discuss developmental biology models (e.g. Danio rerio), pharmalogical models (e.g. Mus musculus) alongside 3D cell biological models (e.g spheroids) and 3D bioprinting methodologies.

Learning Outcomes:

On successful completion of this module, students will: – have an extensive understanding of model systems and their characteristics; – be able to identify the most suitable model for their needs; – have a good knowledge of tissue engineering methodologies; – be able to place model systems according to their field.

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