BMOL30030 Regulation of Gene Expression

BMOL30030 Regulation of Gene Expression

BMOL30030 Regulation of Gene Expression 150 150 Peter

BMOL30030 Regulation of Gene Expression

Academic Year 2021/2022

This module will be an advanced course on the transmission of genetic information. The primary focus will be to obtain a detailed understanding of the general and more specific mechanisms involved in the control of gene expression in both prokaryotic and in eukaryotic systems. The course will begin with the general mechanism of transcription, RNA polymerases and the various classes of transcription factors. Thereafter, specific aspects pertaining to general and specialised mechanisms of gene expression and transcriptional regulation in various prokaryotic and eukaryotic systems will be examined. This module is highly recommended for students intending to take GENE40030 in Stage 4.

Learning Outcomes:

On completion of this module students should be able to:· Explain the fundamental mechanisms of transcription in prokaryotes and eukaryotes,· Explain the main factors regulating gene expression in those systems,· Through specific examples, describe various transcriptional regulatory mechanisms in either prokaryotes or eukaryotes,· Through specific examples and/or through laboratory-based practicals, describe the experimental approaches to investigate the control of gene expression in prokaryotes and/or eukaryotes.

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